Author's response to reviews Title: Longitudinal analysis of vertebral fracture and BMD in a Canadian cohort of adult cystic fibrosis patients Authors:

Author's response to reviews Title: Use of Anthropometric Indicators in Screening for Undiagnosed Vertebral Fractures: A Cross-sectional Analysis of the Fukui Osteoporosis Cohort (FOC) Study Authors:

Author's response to reviews Title: Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype Authors:

Title: Lubiprostone ameliorates the cystic fibrosis mouse intestinal phenotype Author's response to reviews: see over We thank the reviewers for their insightful and constructive comments. The manuscript has been revised in accord with these comments, and we believe the paper has been improved in the process. We hope that our manuscript is now acceptable for BMC Gastroenterology. 1. Introductio...

Author's response to reviews Title: Health-related quality of life after vertebral or hip fracture: a seven-year follow-up study Authors:

Title: Health-related quality of life after vertebral or hip fracture: a seven-year follow-up study

Low Bone Mineral Density and Associated Factors in Patients with Cystic Fibrosis: A Cross-Sectional Study

Background: Failure to maintain bone mass density is a major complication in patients with cystic fibrosis (CF). This study was conducted to evaluate the prevalence of low bone mineral density (BMD) and also identifying associated risk factors in CF patients. Materials and Methods: Present study conducted on 59 CF patients aged 5-35 years referred to respiratory clinic of Masih Daneshvari Hospi...

Author's response to reviews Title: FRAX (R) tool, the WHO algorithm to predict osteoporotic fractures: an analysis of its discriminative and predictive ability in a Spanish female cohort (FRIDEX). Authors:

Conclusions, page 4. Conclusions FRAX without BMD for major and hip fracture demonstrates a good discriminative capacity with the AUC ROC for Spanish women but its predictive capacity does not adjust well with the current algorithm leading to under diagnosis for major fracture and hip fractures. Simple models based on age or BMD alone predicted 10-year risk of major and hip osteoporotic fractur...